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IMPORTANT INFORMATION regarding prescription Non-Steroidal AntiInflammatory Drugs (NSAIDs) such as Rimadyl (carprofen), Etogesic (etodolac), Deramaxx (deracoxib), Metacam (meloxicam), Previcox (firocoxib), and Zubrin (tepoxalin).

*Please read all of the following carefully for the sake of your pet's life and health.

Let your veterinarian know if your pet has been vomiting, having diarrhea, or passing black stools before an NSAID is prescribed for your pet and/or before administering an NSAID to your pet.  

Let your veterinarian know if your pet has been taking other prescription NSAIDs (including sulfasalazine (Azulfidine), piroxicam, phenylbutazone ('Bute'), flunixin meglumine (Banamine), or any of the above listed NSAIDs), or any over-the-counter NSAID products such as aspirin, Pepto Bismol, or Kao Pectate before an NSAID is prescribed for your pet and/or before administering an NSAID to your pet.

Let your veterinarian know if your pet has recently been taking prednisone, other oral catabolic steroid medications such as dexamethasone, prednisolone (including Temaril-P), triamcinolone, methylprednisolone, or hydrocortisone, or has received a STEROID INJECTION (such as Depo Medrol (methylprednisolone acetate), Solu Medrol (methylprednisolone sodium succinate), dexamethasone, dexamethasone sodium phosphate, triamcinolone, Solu Delta Cortef (prednisolone sodium succinate) in the last three months.

Let your veterinarian know if your pet has ever experienced any health related problems from previously administered NSAID medications, before an NSAID is prescribed and/or before you administer an NSAID to your pet.

Stop giving NSAIDs and call or visit a veterinarian quickly if vomiting, diarrhea, or black stools develop.  Stomach and/or intestinal inflammation and/or ulceration can occur in any patient taking NSAIDs.  A black color to vomit or stools may indicate bleeding in the stomach or intestines.

Do not give prescription NSAIDs with other NSAIDs, including over-the-counter NSAID products such as aspirin and bismuth subsalicylate preparations (Pepto Bismol, KaoPectate, etc.).

Giving an H2 blocker (such as famotidine (Pepcid AC), cimetidine (Tagamet HB), or ranitidine (Zantac), while giving the NSAID may help reduce your pet's risks for developing stomach inflammation and/or ulceration while on NSAIDs.  ASK YOUR VETERINARIAN for a proper dose and frequency before giving an H2 blocker.  If advised by your pet's doctor, you should usually continue giving the H2 blocker for a few days after you have finished giving the NSAID.

LIVER TESTING is STRONGLY advised before your pet takes a prescription NSAID.  A few animals will have normal liver tests but still experience life threatening liver disease after taking a prescription NSAID, even for a short period of time.  Pets on long term courses of NSAIDs should have a blood test to assess liver health every three months for safety purposes.  In our experience, nearly all patients can receive a single dose of a prescription NSAID with no adverse effects and without the need for liver testing first.

Never give Tylenol (acetaminophen) or ibuprofen to your pet unless your veterinarian has specifically authorized it.  Tylenol is very poisonous to cats.    Cats are very sensitive to many NSAIDs and NSAIDs are typically used very sparingly and conservatively in cats.  Onsior  has been approved by the FDA for use in cats for a maximum of three days' use.  Baby aspirin is sometimes used at low doses in cats to prevent blood clots related to heart problems.

Additional specific information on the particular NSAID product your pet has been prescribed can often be found on the manufacturers' websites.  Pfizer makes Rimadyl (carprofen), Novartis makes Deramaxx (deracoxib), Boehringer Ingelheim Vetmedica/Merial makes Metacam (meloxicam), Merial makes Previcox (firocoxib), Fort Dodge makes              Etogesic (etodolac) and Schering-Plough makes Zubrin (tepoxalin).  Package inserts (or copies) can be provided for those wishing more extensive information about the particular NSAID prescribed for their pet.

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